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Among LPO products, 4-HNE is particularly relevant due to its ability to form covalent adducts with proteins, thereby disrupting cellular function and promoting inflammation

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A recent study by Rahdar and colleagues (2024) demonstrated that repeated administration of the 5-HT 7 receptor agonist (LP-211) can significantly reduce stereotypical behaviors and improve motor coordination and recognition of new objects in VPA-exposed rats [62]